HIV and Venous Thrombotic Events (Clinical Report) - South African Journal of Surgery

HIV and Venous Thrombotic Events (Clinical Report)

By South African Journal of Surgery

  • Release Date: 2009-05-01
  • Genre: Health & Fitness
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HIV and Venous Thrombotic Events (Clinical Report) by South African Journal of Surgery epub - ebook - audiobook

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HIV infection has been recognised as a prothrombotic condition, with the first isolated case reports of the association between venous thrombo-embolism (VTE) and HIV infection starting to appear in the late 1980s. This association has now been conclusively proven by a large number of studies, the first significant study by Hassell et al. (1) in 1994 reporting an incidence of deep-vein thrombosis (DVT) of 18% in a group of 60 HIV-positive patients. A systematic review published in 2005 found an incidence ranging from 0.19% to 18%. (2) This incidence is well in excess of what one would expect in a non-infected population, where the average risk of developing DVT is reported to be approximately 5/10 000. (3) As a consequence of the high number of HIV-infected individuals in southern Africa (in South Africa it is estimated that there are 5.7 million HIV-positive individuals out of a total population of 44 million (4)), HIV-related thrombosis is an important aspect of this disease. In an audit performed at Johannesburg Hospital, 84% of patients who presented with DVT were found to be HIV positive. (5)

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